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codon optimized nucleotide sequences for filc  (Sangon Biotech)

 
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    Structured Review

    Sangon Biotech codon optimized nucleotide sequences for filc
    Structural representations of <t>FilC</t> and PD-1 proteins (a) FilC – Structural model of the FilC protein, depicting its folded β -sheet arrangement. (b) PD-1 – Structural model of the PD-1 immune checkpoint receptor.
    Codon Optimized Nucleotide Sequences For Filc, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/codon+optimized+nucleotide+sequences+for+filc/pmc12450999-104-0-22?v=Sangon+Biotech
    Average 86 stars, based on 1 article reviews
    codon optimized nucleotide sequences for filc - by Bioz Stars, 2026-07
    86/100 stars

    Images

    1) Product Images from "Novel immune checkpoint inhibitor FilC/PD-1 recombinant vaccinia virus inhibits hepatocellular carcinoma"

    Article Title: Novel immune checkpoint inhibitor FilC/PD-1 recombinant vaccinia virus inhibits hepatocellular carcinoma

    Journal: Frontiers in Medicine

    doi: 10.3389/fmed.2025.1622209

    Structural representations of FilC and PD-1 proteins (a) FilC – Structural model of the FilC protein, depicting its folded β -sheet arrangement. (b) PD-1 – Structural model of the PD-1 immune checkpoint receptor.
    Figure Legend Snippet: Structural representations of FilC and PD-1 proteins (a) FilC – Structural model of the FilC protein, depicting its folded β -sheet arrangement. (b) PD-1 – Structural model of the PD-1 immune checkpoint receptor.

    Techniques Used:

    Structural quality assessment of FilC and PD-1 Models (a) FilC Model Validation: Various structural validation metrics, including Rfree, Clashscore, Ramachandran outliers, Sidechain outliers, and RSRZ outliers, are shown. The percentile ranks are indicated relative to all X-ray structures and those with similar resolution. (b) PD-1 Model Validation: Quality assessment of the PD-1 structural model based on Clashscore, Ramachandran outliers, and sidechain outliers. The percentile ranks are provided relative to all NMR structures.
    Figure Legend Snippet: Structural quality assessment of FilC and PD-1 Models (a) FilC Model Validation: Various structural validation metrics, including Rfree, Clashscore, Ramachandran outliers, Sidechain outliers, and RSRZ outliers, are shown. The percentile ranks are indicated relative to all X-ray structures and those with similar resolution. (b) PD-1 Model Validation: Quality assessment of the PD-1 structural model based on Clashscore, Ramachandran outliers, and sidechain outliers. The percentile ranks are provided relative to all NMR structures.

    Techniques Used: Biomarker Discovery

    Brightfield and fluorescence microscopy images showing vaccinia virus–mediated transgene expression. (a) Brightfield image and (b) corresponding fluorescence image of HepG2 hepatocellular carcinoma cells 24 h post-infection with vv-PD-1/FilC at an MOI of X pfu/cell. Red fluorescence indicates reporter expression (e.g., mCherry) under the control of the viral promoter. Scale bars: 50 μm. (a) Brightfield image showing Hepa1-6 cell morphology 24 h after infection. (b) Corresponding fluorescence microscopy image illustrating strong transgene expression (red fluorescence), indicating efficient viral infection and gene delivery.
    Figure Legend Snippet: Brightfield and fluorescence microscopy images showing vaccinia virus–mediated transgene expression. (a) Brightfield image and (b) corresponding fluorescence image of HepG2 hepatocellular carcinoma cells 24 h post-infection with vv-PD-1/FilC at an MOI of X pfu/cell. Red fluorescence indicates reporter expression (e.g., mCherry) under the control of the viral promoter. Scale bars: 50 μm. (a) Brightfield image showing Hepa1-6 cell morphology 24 h after infection. (b) Corresponding fluorescence microscopy image illustrating strong transgene expression (red fluorescence), indicating efficient viral infection and gene delivery.

    Techniques Used: Fluorescence, Microscopy, Virus, Expressing, Infection, Control

    Time-dependent viral replication kinetics of the FilC/PD-1 recombinant vaccinia virus in HCC and non-cancerous cell lines. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test; error bars represent SD ( n = 3); p < 0.01 compared to non-HCC cell lines at 48 h and 72 h.
    Figure Legend Snippet: Time-dependent viral replication kinetics of the FilC/PD-1 recombinant vaccinia virus in HCC and non-cancerous cell lines. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test; error bars represent SD ( n = 3); p < 0.01 compared to non-HCC cell lines at 48 h and 72 h.

    Techniques Used: Recombinant, Virus

    Differential gene expression between FilC/PD-1–treated tumors and controls.
    Figure Legend Snippet: Differential gene expression between FilC/PD-1–treated tumors and controls.

    Techniques Used: Gene Expression



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    codon optimized nucleotide sequences for filc  (Sangon Biotech)
    86
    Sangon Biotech codon optimized nucleotide sequences for filc
    Structural representations of <t>FilC</t> and PD-1 proteins (a) FilC – Structural model of the FilC protein, depicting its folded β -sheet arrangement. (b) PD-1 – Structural model of the PD-1 immune checkpoint receptor.
    Codon Optimized Nucleotide Sequences For Filc, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/codon+optimized+nucleotide+sequences+for+filc/pmc12450999-104-0-22?v=Sangon+Biotech
    Average 86 stars, based on 1 article reviews
    codon optimized nucleotide sequences for filc - by Bioz Stars, 2026-07
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Structural representations of FilC and PD-1 proteins (a) FilC – Structural model of the FilC protein, depicting its folded β -sheet arrangement. (b) PD-1 – Structural model of the PD-1 immune checkpoint receptor.

    Journal: Frontiers in Medicine

    Article Title: Novel immune checkpoint inhibitor FilC/PD-1 recombinant vaccinia virus inhibits hepatocellular carcinoma

    doi: 10.3389/fmed.2025.1622209

    Figure Lengend Snippet: Structural representations of FilC and PD-1 proteins (a) FilC – Structural model of the FilC protein, depicting its folded β -sheet arrangement. (b) PD-1 – Structural model of the PD-1 immune checkpoint receptor.

    Article Snippet: Codon-optimized nucleotide sequences for FilC (GenBank accession no. OR123456 ) and the PD-1 inhibitor (GenBank accession no. OR123457 ) were synthesized by Sangon Biotech (Shanghai, China) and verified by Sanger sequencing prior to cloning.

    Techniques:

    Structural quality assessment of FilC and PD-1 Models (a) FilC Model Validation: Various structural validation metrics, including Rfree, Clashscore, Ramachandran outliers, Sidechain outliers, and RSRZ outliers, are shown. The percentile ranks are indicated relative to all X-ray structures and those with similar resolution. (b) PD-1 Model Validation: Quality assessment of the PD-1 structural model based on Clashscore, Ramachandran outliers, and sidechain outliers. The percentile ranks are provided relative to all NMR structures.

    Journal: Frontiers in Medicine

    Article Title: Novel immune checkpoint inhibitor FilC/PD-1 recombinant vaccinia virus inhibits hepatocellular carcinoma

    doi: 10.3389/fmed.2025.1622209

    Figure Lengend Snippet: Structural quality assessment of FilC and PD-1 Models (a) FilC Model Validation: Various structural validation metrics, including Rfree, Clashscore, Ramachandran outliers, Sidechain outliers, and RSRZ outliers, are shown. The percentile ranks are indicated relative to all X-ray structures and those with similar resolution. (b) PD-1 Model Validation: Quality assessment of the PD-1 structural model based on Clashscore, Ramachandran outliers, and sidechain outliers. The percentile ranks are provided relative to all NMR structures.

    Article Snippet: Codon-optimized nucleotide sequences for FilC (GenBank accession no. OR123456 ) and the PD-1 inhibitor (GenBank accession no. OR123457 ) were synthesized by Sangon Biotech (Shanghai, China) and verified by Sanger sequencing prior to cloning.

    Techniques: Biomarker Discovery

    Brightfield and fluorescence microscopy images showing vaccinia virus–mediated transgene expression. (a) Brightfield image and (b) corresponding fluorescence image of HepG2 hepatocellular carcinoma cells 24 h post-infection with vv-PD-1/FilC at an MOI of X pfu/cell. Red fluorescence indicates reporter expression (e.g., mCherry) under the control of the viral promoter. Scale bars: 50 μm. (a) Brightfield image showing Hepa1-6 cell morphology 24 h after infection. (b) Corresponding fluorescence microscopy image illustrating strong transgene expression (red fluorescence), indicating efficient viral infection and gene delivery.

    Journal: Frontiers in Medicine

    Article Title: Novel immune checkpoint inhibitor FilC/PD-1 recombinant vaccinia virus inhibits hepatocellular carcinoma

    doi: 10.3389/fmed.2025.1622209

    Figure Lengend Snippet: Brightfield and fluorescence microscopy images showing vaccinia virus–mediated transgene expression. (a) Brightfield image and (b) corresponding fluorescence image of HepG2 hepatocellular carcinoma cells 24 h post-infection with vv-PD-1/FilC at an MOI of X pfu/cell. Red fluorescence indicates reporter expression (e.g., mCherry) under the control of the viral promoter. Scale bars: 50 μm. (a) Brightfield image showing Hepa1-6 cell morphology 24 h after infection. (b) Corresponding fluorescence microscopy image illustrating strong transgene expression (red fluorescence), indicating efficient viral infection and gene delivery.

    Article Snippet: Codon-optimized nucleotide sequences for FilC (GenBank accession no. OR123456 ) and the PD-1 inhibitor (GenBank accession no. OR123457 ) were synthesized by Sangon Biotech (Shanghai, China) and verified by Sanger sequencing prior to cloning.

    Techniques: Fluorescence, Microscopy, Virus, Expressing, Infection, Control

    Time-dependent viral replication kinetics of the FilC/PD-1 recombinant vaccinia virus in HCC and non-cancerous cell lines. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test; error bars represent SD ( n = 3); p < 0.01 compared to non-HCC cell lines at 48 h and 72 h.

    Journal: Frontiers in Medicine

    Article Title: Novel immune checkpoint inhibitor FilC/PD-1 recombinant vaccinia virus inhibits hepatocellular carcinoma

    doi: 10.3389/fmed.2025.1622209

    Figure Lengend Snippet: Time-dependent viral replication kinetics of the FilC/PD-1 recombinant vaccinia virus in HCC and non-cancerous cell lines. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test; error bars represent SD ( n = 3); p < 0.01 compared to non-HCC cell lines at 48 h and 72 h.

    Article Snippet: Codon-optimized nucleotide sequences for FilC (GenBank accession no. OR123456 ) and the PD-1 inhibitor (GenBank accession no. OR123457 ) were synthesized by Sangon Biotech (Shanghai, China) and verified by Sanger sequencing prior to cloning.

    Techniques: Recombinant, Virus

    Differential gene expression between FilC/PD-1–treated tumors and controls.

    Journal: Frontiers in Medicine

    Article Title: Novel immune checkpoint inhibitor FilC/PD-1 recombinant vaccinia virus inhibits hepatocellular carcinoma

    doi: 10.3389/fmed.2025.1622209

    Figure Lengend Snippet: Differential gene expression between FilC/PD-1–treated tumors and controls.

    Article Snippet: Codon-optimized nucleotide sequences for FilC (GenBank accession no. OR123456 ) and the PD-1 inhibitor (GenBank accession no. OR123457 ) were synthesized by Sangon Biotech (Shanghai, China) and verified by Sanger sequencing prior to cloning.

    Techniques: Gene Expression